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The molecular epidemiology of varicella-zoster virus: evidence for geographic segregation.
Quinlivan, Mark; Hawrami, Khidir; Barrett-Muir, Winsome; Aaby, Peter; Arvin, Ann; Chow, Vincent T; John, T Jacob; Matondo, Patrick; Peiris, Malik; Poulsen, Anja; Siqueira, Marilda; Takahashi, Michiaki; Talukder, Yamima; Yamanishi, Koichi; Leedham-Green, Mary; Scott, Fiona T; Thomas, Sara L; Breuer, Judith.
Afiliación
  • Quinlivan M; Department of Medical Microbiology, School of Medicine, Queen Mary College, London, United Kingdom.
J Infect Dis ; 186(7): 888-94, 2002 Oct 01.
Article en En | MEDLINE | ID: mdl-12232828
Of 75 varicella-zoster virus (VZV) isolates obtained from patients in Africa, Asia, and the Far East, 74 (98.6%) were found to be positive for a BglI restriction site in gene 54. By contrast, <22% of strains from patients in the United Kingdom and in North and South America were positive for the BglI restriction site. Viruses positive for BglI were significantly more common in zoster occurring in patients of nonwhite origin (P<.05). Irrespective of the country in which the sample was obtained, 98% of strains positive for BglI clustered within a single phylogenetic group, which we termed "group A"; the exception was 1 strain that appeared to be recombinant genotype C/A. We used the BglI site to examine both the spread of type A viruses in the United Kingdom and the patterns of VZV infections within persons from different ethnic groups who grew up in the United Kingdom or abroad.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Varicela / Herpesvirus Humano 3 / Herpes Zóster Tipo de estudio: Screening_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Africa / America do norte / America do sul / Asia / Europa Idioma: En Revista: J Infect Dis Año: 2002 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Buscar en Google
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Varicela / Herpesvirus Humano 3 / Herpes Zóster Tipo de estudio: Screening_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Africa / America do norte / America do sul / Asia / Europa Idioma: En Revista: J Infect Dis Año: 2002 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos