Your browser doesn't support javascript.
loading
Partial laryngectomy to treat early glottic cancer after failure of radiation therapy.
Toma, Makiko; Nibu, Ken-Ichi; Nakao, Kazunari; Matsuzaki, Masaki; Mochiki, Masato; Yuge, Tadashi; Terahara, Atsuro; Sugasawa, Masashi.
Afiliación
  • Toma M; Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Japan. makiko@jd5.so-net.ne.jp
Arch Otolaryngol Head Neck Surg ; 128(8): 909-12, 2002 Aug.
Article en En | MEDLINE | ID: mdl-12162769
OBJECTIVE: To evaluate the role of partial laryngectomy to treat glottic cancer after failure of radiation therapy. DESIGN: A 12-year retrospective outcome analysis. SETTING: University referral center. PATIENTS: A total of 19 patients who underwent partial laryngectomy to treat glottic cancer after failure of radiation therapy. RESULTS: The follow-up period in this group ranged from 31 to 144 months. After surgery, a laryngocutaneous fistula was observed in 4 cases, and flap necrosis occurred in 2, but these complications were successfully managed. Maximum phonation time after surgery ranged from 3 to 28 seconds (median phonation time, 10.2 seconds). Of these 19 patients, 3 developed local recurrence. These cases were successfully treated with total laryngectomy. A surgical margin of less than 1 mm was found to be a significant risk factor for local recurrence after partial laryngectomy. CONCLUSIONS: These results indicate that partial laryngectomy is a useful option for the treatment of irradiation failure in the treatment of stage I and stage II vocal cord carcinomas. However, careful follow-up is mandatory for patients with a small surgical margin.
Asunto(s)
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Carcinoma de Células Escamosas / Neoplasias Laríngeas / Glotis / Laringectomía / Recurrencia Local de Neoplasia Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Arch Otolaryngol Head Neck Surg Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2002 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Carcinoma de Células Escamosas / Neoplasias Laríngeas / Glotis / Laringectomía / Recurrencia Local de Neoplasia Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Arch Otolaryngol Head Neck Surg Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2002 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos