Cytokeratins expression of constituting cells in ameloblastoma.
Bull Tokyo Dent Coll
; 43(1): 13-21, 2002 Feb.
Article
en En
| MEDLINE
| ID: mdl-12013821
The purposes of this study were to investigate the distribution of cytokeratins in the different tissue types of ameloblastoma and to discuss the histogenesis of this tumor. CK19 and CK8, which are markers for odontogenic epithelium, reacted positively to the constituting cells in all types of ameloblastoma. This suggests that all types of ameloblastoma derive from odontogenic epithelium. However, the desmoplastic type diminished the odontogenic characteristics because the basal cells are negative to CK19. Immunoreactions of five kinds of cytokeratin revealed similar results in plexiform, follicular, acanthomatous, and granular cell types. The plexiform type is probably the original type of ameloblastoma; the other types have the characteristics of squamous epithelium, and the follicular, acanthomatous, and granular cell types can develop due to the differentiation of cells of the plexiform type into squamous epithelium.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ameloblastoma
/
Neoplasias Maxilomandibulares
/
Células Epiteliales
/
Queratinas
Límite:
Humans
Idioma:
En
Revista:
Bull Tokyo Dent Coll
Año:
2002
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Japón