Thygeson lecture. Amniotic membrane transplantation: why is it effective?
Cornea
; 21(4): 339-41, 2002 May.
Article
en En
| MEDLINE
| ID: mdl-11973378
PURPOSE: To review the uses and previously proposed mechanisms of action of amniotic membrane transplantation (AMT) and to suggest a new mechanism of action for the effectiveness of AMT in resolving a persistent epithelial defect (PED). METHODS: Significant clinical and experimental publications are reviewed. RESULTS: Evidence from the scientific literature suggests a new hypothesis for the effectiveness of AMT in the reepithelialization of a PED and the reduction of corneal stromal inflammation and continued fibrosis. CONCLUSION: It is suggested that reepithelialization of a PED, and hence the reduction of stromal inflammation and continued fibrosis following reepithelialization, is aided by the combination of oxygenation, moisture and protection of the fragile epithelium by the amniotic membrane.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Córnea
/
Amnios
Idioma:
En
Revista:
Cornea
Año:
2002
Tipo del documento:
Article
Pais de publicación:
Estados Unidos