[Experimental models of angiogenesis (in vitro and in vivo)]. / Modèles expérimentaux d'angiogénèse (in vitro et chez l'animal).
Therapie
; 56(5): 473-81, 2001.
Article
en Fr
| MEDLINE
| ID: mdl-11806283
The multiplicity of experimental models of angiogenesis in vitro and in vivo complicates the choice of a straightforward strategy to accurately identify the anti-angiogenic potential of a natural or synthetic compound with antitumoral activity. In the absence of such consensus, it is clear that the demonstration of an activity lies in the use of several models, both in vitro and in vivo. A rapid overview of the most currently used models, especially in vitro, is presented, with an emphasis on their limitations. Several examples of research strategies for identifying antitumoral anti-angiogenic compounds are used in illustration.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neovascularización Fisiológica
Límite:
Animals
/
Humans
Idioma:
Fr
Revista:
Therapie
Año:
2001
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Francia