Modulation of caudal intestinal permeability in the rat during infection by the tapeworm Hymenolepis diminuta.
J Parasitol
; 87(6): 1260-3, 2001 Dec.
Article
en En
| MEDLINE
| ID: mdl-11780808
Bidirectional movement of solutes between the intestinal lumen and systemic circulation is restricted by tissue barriers that may be altered under conditions such as intestinal infection. In a study using an in vitro everted sac preparation to assess small intestinal permeability in a lumen-to-serosa direction, 51Cr-EDTA movement was compared regionally in the jejunum and ileum of rats infected and uninfected by tapeworms. Whereas jejunal segments showed no significant differences in permeability to 51Cr-EDTA at 6, 15, or 32 days postinfection (dpi), ileal segments displayed an increased permeability on 15 and 32 dpi, but not 6 dpi. The alterations in permeability were not reversed 1 wk after removal of the tapeworm from the intestine. In conclusion, the strictly lumen-dwelling tapeworm infection allows increased movement of molecules from the lumen into ileal, but not jejunal, tissues by 15 dpi.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Himenolepiasis
/
Intestinos
Límite:
Animals
Idioma:
En
Revista:
J Parasitol
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos