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The "common cause hypothesis" of cognitive aging: evidence for not only a common factor but also specific associations of age with vision and grip strength in a cross-sectional analysis.
Christensen, H; Mackinnon, A J; Korten, A; Jorm, A F.
Afiliación
  • Christensen H; Centre for Mental Health Research, Australian National University, Canberra, Australian Capital Territory, Australia.
Psychol Aging ; 16(4): 588-99, 2001 Dec.
Article en En | MEDLINE | ID: mdl-11766914
A prominent hypothesis in cognitive aging is the existence of a common factor that is responsible for age-related deterioration in cognitive and noncognitive processes. A multiple indicators, multiple causes model was used to examine the nature of this common factor and its relationship to age, gender, and the apolipoprotein E (APOE) genotype. The common factor was modeled by using 10 indicator variables with 374 participants aged between 77.4 and 98.7 years. A latent factor was identified, with all indicators except blood pressure loading significantly. This factor could be established in 2 age strata within the sample. After controlling for the effects of gender, APOE, and level of education, direct effects of age were seen on visual functioning and grip strength. APOE was significantly associated with memory but not with the common factor. The findings suggest that a number of specific processes may operate concurrently with any common cause factor.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de la Visión / Envejecimiento / Trastornos del Conocimiento / Fuerza de la Mano Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Psychol Aging Asunto de la revista: GERIATRIA / PSICOLOGIA Año: 2001 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de la Visión / Envejecimiento / Trastornos del Conocimiento / Fuerza de la Mano Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Psychol Aging Asunto de la revista: GERIATRIA / PSICOLOGIA Año: 2001 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos