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Commercial diet induced hypothyroidism due to high iodine. A histological and radiological analysis.
Castillo, V A; Pisarev, M A; Lalia, J C; Rodriguez, M S; Cabrini, R L; Márquez, G.
Afiliación
  • Castillo VA; School Hospital-Endocrinology Service, Faculty of Veterinary Science, University of Buenos Aires, Argentina. vcastill@fvet.uba.ar
Vet Q ; 23(4): 218-23, 2001 Nov.
Article en En | MEDLINE | ID: mdl-11765244
A number of puppies of the School Hospital of the Faculty of Veterinary Science-UBA showed bone changes. Measurement of the iodine content of the commercial diet showed a significant increase in its content. Iodine excess causes alterations in thyroid function and morphology, and its hormones have a direct action on bone formation. Three groups of puppies were fed on different diets: a home-prepared diet, a commercial diet (containing 5.6 mg potassium iodide/kg dry food), and a home-prepared diet supplemented with 5.6 mg potassium iodide/kg dry food. Groups B and C developed hypothyroidism. A significant decrease (p<0.05) in the styloid apophyseal surface was found in groups B and C vs. A, determined by radiography. Histologically, the hypertrophied cartilage was shorter in groups B and C than in group A (p<0.0001). The present results suggest that commercial diets with a high iodine content may cause hypothyroidism and changes in bone metabolism.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de los Perros / Miembro Anterior / Hipotiroidismo / Yodo / Alimentación Animal Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Vet Q Año: 2001 Tipo del documento: Article País de afiliación: Argentina Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades de los Perros / Miembro Anterior / Hipotiroidismo / Yodo / Alimentación Animal Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Revista: Vet Q Año: 2001 Tipo del documento: Article País de afiliación: Argentina Pais de publicación: Reino Unido