Your browser doesn't support javascript.
loading
Expression of bone morphogenetic protein-5 gene during chick heart development: possible roles in valvuloseptal endocardial cushion formation.
Yamagishi, T; Nakajima, Y; Nishimatsu, S; Nohno, T; Ando, K; Nakamura, H.
Afiliación
  • Yamagishi T; Department of Anatomy, Saitama Medical School, Moroyama-machi, Iruma-gun, Saitama, Japan. toshiy@saitama-u.ac.jp
Anat Rec ; 264(4): 313-6, 2001 12 01.
Article en En | MEDLINE | ID: mdl-11745086
The bone morphogenetic protein (BMP) family, comprising multifunctional peptide growth factors, regulates many developmental processes in a variety of tissues. We examined the spatiotemporal expression of BMP5 by in situ hybridization in chick embryonic hearts from stages 5 to 33. The BMP5 gene was first expressed in the endoderm underlying the precardiac mesoderm at stages 5 to 8. Thereafter, BMP5 expression was restricted to the myocardium of the atrioventricular (AV) canal and outflow tract (OT) regions, where the valvuloseptal endocardial cushion tissue is induced. These results suggest that BMP5 may play important roles not only in myocardial differentiation, but also in the formation and maintenance of endocardial cushion tissue.
Asunto(s)
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Morfogenéticas Óseas / Endocardio / Corazón / Tabiques Cardíacos / Válvulas Cardíacas Límite: Animals Idioma: En Revista: Anat Rec Año: 2001 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos
Buscar en Google
Añadir a Mi BVS
Imprimir
XML
PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Morfogenéticas Óseas / Endocardio / Corazón / Tabiques Cardíacos / Válvulas Cardíacas Límite: Animals Idioma: En Revista: Anat Rec Año: 2001 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos