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Lateralization of minicolumns in human planum temporale is absent in nonhuman primate cortex.
Buxhoeveden, D P; Switala, A E; Litaker, M; Roy, E; Casanova, M F.
Afiliación
  • Buxhoeveden DP; Medical College of Georgia, Downtown VA Medical Center, Psychiatry Service, Augusta, Ga. 30904, USA. danb@psych.mcg.edu
Brain Behav Evol ; 57(6): 349-58, 2001 Jun.
Article en En | MEDLINE | ID: mdl-11713389
Gross analyses of large brain areas, as in MRI studies of macroanatomical structures, average subtle alterations in small regions, inadvertently missing significant anomalies. We developed a computerized imaging program to microscopically examine minicolumns and used it to study Nissl-stained slides of normal human, chimpanzee, and rhesus monkey brains in a region of the planum temporale. With this method, we measured the width of cell columns, the peripheral neuropil space, the spacing density of neurons within columns, and the Gray Level index per minicolumn. Only human brain tissue revealed robust asymmetry in two aspects of minicolumn morphology: wider columns and more neuropil space on the left side. This asymmetry was absent in chimpanzee and rhesus monkey brains.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lóbulo Temporal / Pan troglodytes / Dominancia Cerebral / Evolución Biológica / Macaca mulatta Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Brain Behav Evol Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lóbulo Temporal / Pan troglodytes / Dominancia Cerebral / Evolución Biológica / Macaca mulatta Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Brain Behav Evol Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza