Iatrogenic painful neuropathic complications of surgery in cancer.
Acta Anaesthesiol Scand
; 45(9): 1090-4, 2001 Oct.
Article
en En
| MEDLINE
| ID: mdl-11683658
It is estimated that at least one out of four patients with cancer complains of pain originating from nerve injury. Nerve injury may result from direct invasion/compression by tumour, or by remote effect of the cancer such as paraneoplastic polyneuropathy. In many cases, the nerve injury is caused by medical therapy, or surgical interventions. Pain generated by drugs or medical acts is called iatrogenic. A common iatrogenic neuralgia is chemotherapy induced painful polyneuropathy. This neuropathy typically affects mostly the small myelinated and unmyelinated nerve fibres. Surgical and anaesthesiological interventions also frequently cause direct nerve stretch or section. Some interventions, particularly those requiring extended resection, have a higher incidence of painful sequelae. Limb and colon amputation, nerve dissection, mastectomy and thoracotomy are the most common interventions for cancer known to cause nerve injury. As pain clinicians, we focus attention on the painful consequences of surgical interventions because there is evidence that a more accurate surgical approach and possibly a prophylactic prevention of the neuralgia may reduce the painful sequelae of nerve injury.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dolor
/
Dolor Postoperatorio
/
Enfermedades del Sistema Nervioso Periférico
/
Enfermedad Iatrogénica
/
Neoplasias
Límite:
Humans
Idioma:
En
Revista:
Acta Anaesthesiol Scand
Año:
2001
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Reino Unido