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Coeliac disease, anaemia and pregnancy.
Haslam, N; Lock, R J; Unsworth, D J.
Afiliación
  • Haslam N; Department of Gastroenterology, Bury General Hospital, Lancashire, United Kingdom.
Clin Lab ; 47(9-10): 467-9, 2001.
Article en En | MEDLINE | ID: mdl-11596908
We have investigated the prevalence of positive serology for coeliac disease in pregnant women, using the IgA anti-endomysium antibody test. Five of 216 pregnant women with a haemoglobin less than 11 g/dl were positive, compared to 0/350 with haemoglobin > or = 11 g/dl. Four of these five had low plasma ferritin levels, indicative of iron deficiency anaemia; the fifth was borderline normal. We found no association between positive coeliac disease serology and folate deficiency. None of thirty mothers of children born with neural tube defects were IgA anti-endomysium antibody positive. This study has identified a very high prevalence of occult coeliac disease in pregnancy and a strong association with anaemia. We advise that in cases with a haemoglobin of less than 11 g/dl in pregnancy, coeliac disease should be excluded.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Complicaciones Hematológicas del Embarazo / Enfermedad Celíaca / Anemia Ferropénica Tipo de estudio: Diagnostic_studies / Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Middle aged / Pregnancy Idioma: En Revista: Clin Lab Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2001 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Alemania
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones del Embarazo / Complicaciones Hematológicas del Embarazo / Enfermedad Celíaca / Anemia Ferropénica Tipo de estudio: Diagnostic_studies / Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Middle aged / Pregnancy Idioma: En Revista: Clin Lab Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2001 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Alemania