Acute sensory ataxic neuropathy associated with monospecific anti-GD1b IgG antibody.

Pan, C L; Yuki, N; Koga, M; Chiang, M C; Hsieh, S T

Pan, C L; Yuki, N; Koga, M; Chiang, M C; Hsieh, S T.

Afiliación

Pan CL; Department of Neurology, National Taiwan University Hospital, Taipei.

Neurology ; 57(7): 1316-8, 2001 Oct 09.

Article en En | MEDLINE | ID: mdl-11591857

RESUMEN

The authors describe two patients with acute sensory ataxic neuropathy. Both had a profound loss of proprioception and generalized areflexia. High titers of monospecific anti-GD1b IgG antibody were detected in their sera during the acute phase. Sensory ataxia resolved within 2 weeks after the onset. Taken together with the induction of experimental sensory ataxic neuropathy sensitized with GD1b ganglioside, GD1b may be a target molecule for autoantibody in some patients with acute sensory ataxic neuropathy.

Asunto(s)

Ataxia/inmunología; Gangliósidos/inmunología; Inmunoglobulina G/sangre; Enfermedad Aguda; Adulto; Especificidad de Anticuerpos; Femenino; Humanos; Masculino; Persona de Mediana Edad; Conducción Nerviosa; Neuronas Aferentes/fisiología

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ataxia / Inmunoglobulina G / Gangliósidos Tipo de estudio: Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Neurology Año: 2001 Tipo del documento: Article Pais de publicación: Estados Unidos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links