Probabilistic contingency learning with limbic or prefrontal damage.
Behav Neurosci
; 115(5): 993-1001, 2001 Oct.
Article
en En
| MEDLINE
| ID: mdl-11584932
A fundamental capacity of the human brain is to learn relations (contingencies) between environmental stimuli and the consequences of their occurrence. Some contingencies are probabilistic; that is, they predict an event in some situations but not in all. Animal studies suggest that damage to limbic structures or the prefrontal cortex may disturb probabilistic learning. The authors studied the learning of probabilistic contingencies in amnesic patients with limbic lesions, patients with prefrontal cortex damage, and healthy controls. Across 120 trials, participants learned contingent relations between spatial sequences and a button press. Amnesic patients had learning comparable to that of control subjects but failed to indicate what they had learned. Across the last 60 trials, amnesic patients and control subjects learned to avoid a noncontingent choice better than frontal patients. These results indicate that probabilistic learning does not depend on the brain structures supporting declarative memory.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aprendizaje por Probabilidad
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Aprendizaje por Asociación
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Daño Encefálico Crónico
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Corteza Prefrontal
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Amnesia
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Sistema Límbico
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Behav Neurosci
Año:
2001
Tipo del documento:
Article
País de afiliación:
Suiza
Pais de publicación:
Estados Unidos