Expression of the Pasteurella multocida ompH gene is negatively regulated by the Fur protein.
FEMS Microbiol Lett
; 203(1): 35-40, 2001 Sep 11.
Article
en En
| MEDLINE
| ID: mdl-11557137
The fur gene of Pasteurella multocida has been cloned by complementation of an Escherichia coli fur mutant. The P. multocida fur gene, which encodes a predicted protein of 147 amino acids, displaying the highest identity (89%) with the same protein of Haemophilus influenzae, is negatively regulated by its own product. By construction of a P. multocida fur mutant, it has been demonstrated that the ompH gene, encoding a major structural protein of the outer membrane, presenting high antigenicity power, is negatively regulated by iron and glucose. Furthermore, wild-type and fur-defective cells of P. multocida show the same level of virulence.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Represoras
/
Proteínas de la Membrana Bacteriana Externa
/
Proteínas Bacterianas
/
Regulación Bacteriana de la Expresión Génica
/
Pasteurella multocida
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
FEMS Microbiol Lett
Año:
2001
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Reino Unido