Helium-ion-induced human cataractogenesis.
Adv Space Res
; 14(10): 501-5, 1994 Oct.
Article
en En
| MEDLINE
| ID: mdl-11539986
Retrospective and ongoing analyses of clinical records from 347 primary intraocular melanoma patients treated with helium ions at LBL will allow examination of the exposure-response data for human cataract; which is a complication of the therapy from incidental exposure of the lens. Direct particle beam traversal of at least a portion of the lens usually is unavoidable in treatment of posterior intraocular tumors. The precise treatment planned for each patient permits quantitative assessment of the lenticular dose and its radiation quality. We are reporting our preliminary results on the development of helium-ion-induced lens opacifications and cataracts in 54 of these patients who had 10% or less of their lens in the treatment field. We believe these studies will be relevant to estimating the human risk for cataract in space flight.
Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Úvea
/
Catarata
/
Helio
/
Cristalino
/
Melanoma
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
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Humans
/
Middle aged
Idioma:
En
Revista:
Adv Space Res
Asunto de la revista:
MEDICINA AEROESPACIAL
Año:
1994
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Reino Unido