Identification, quantification and fine structural characterization of glycosaminoglycans from uterine leiomyoma and normal myometrium.
Biochimie
; 83(6): 529-36, 2001 Jun.
Article
en En
| MEDLINE
| ID: mdl-11506898
The type, amount and fine chemical composition of glycosaminoglycans (GAGs) present both in human normal myometrium and uterine leiomyoma have been studied. GAGs were fractionated by ion-exchange chromatography on DEAE-Sephacel, isolated by gel-permeation chromatography on Sepharose CL-6B and characterized using electrophoresis in cellulose acetate membranes, specific enzymic treatments and analysis by high-performance capillary electrophoresis (HPCE). No statistical intrabatch differences in total GAG content in both tissues were identified, whereas significant interbatch differences between normal myometrium and uterine leiomyoma were recorded. Hyaluronan (HA), chondroitin sulphate (CS), dermatan sulphate (DS), heparan sulphate (HS) and keratan sulphate (KS) were identified in both tissues. Statistically significant (P
Asunto(s)
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Uterinas
/
Glicosaminoglicanos
/
Leiomioma
/
Miometrio
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Biochimie
Año:
2001
Tipo del documento:
Article
País de afiliación:
Grecia
Pais de publicación:
Francia
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Uterinas
/
Glicosaminoglicanos
/
Leiomioma
/
Miometrio
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Biochimie
Año:
2001
Tipo del documento:
Article
País de afiliación:
Grecia
Pais de publicación:
Francia