Obstructive granulomatous bronchiolitis due to Mycobacterium avium complex in an immunocompetent man.

Grimes, M M; Cole, T J; Fowler, A A

Grimes, M M; Cole, T J; Fowler, A A.

Afiliación

Grimes MM; Department of Pathology, Virginia Commonwealth University, Richmond, VA 23298, USA. mgrimes@hsc.vcu.edu

Respiration ; 68(4): 411-5, 2001.

Article en En | MEDLINE | ID: mdl-11464091

RESUMEN

While the development of pulmonary disease due to Mycobacterium avium complex (MAC) infection is most commonly associated with underlying predisposing factors, this organism occasionally causes symptomatic disease in otherwise normal individuals. Patients with MAC pulmonary disease most often present with cavitating granulomas, but a spectrum of pathologic changes has been described. The authors present a case of MAC pulmonary disease in an immunocompetent, middle-aged man with no identified predisposing factors. The diagnostic biopsy disclosed the unusual finding of noncaseating granulomas with predominant involvement of bronchioles, corresponding to the patient's obstructive and restrictive pulmonary dysfunction.

Asunto(s)

Bronquiolitis/microbiología; Granuloma/microbiología; Infección por Mycobacterium avium-intracellulare/complicaciones; Adulto; Bronquiolitis/patología; Granuloma/patología; Humanos; Inmunocompetencia; Masculino; Infección por Mycobacterium avium-intracellulare/patología

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bronquiolitis / Infección por Mycobacterium avium-intracellulare / Granuloma Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Respiration Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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