Environmental monitoring using acetylcholinesterase inhibition in vitro. A case study in two Mexican lagoons.
Mar Environ Res
; 50(1-5): 357-60, 2000.
Article
en En
| MEDLINE
| ID: mdl-11460718
Cholinesterase inhibition is considered a specific biomarker of exposure and effect for organophosphorous pesticides. Its use for monitoring has been hindered, particularly in tropical countries where organophosphates are widely used for malaria and dengue control, because of the frequent lack of suitable controls. An in vitro technique is proposed as a biochemical method for monitoring pollutant mixtures in sediment toxicity tests. Brain homogenate from the fish Oreochromis niloticus is used as the enzyme source. Optimum incubation time, extraction solvent and effect of crude oil on acetylcholinesterase (AChE) are reported. The method described was used in sediments from two Mexican lagoons, located in an oil extraction area where pesticides are used in agriculture and vector control campaigns. AChE inhibitions from 3 to 21% were found in these lagoons, even in the presence of high concentrations of petroleum.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Acetilcolinesterasa
/
Contaminantes Químicos del Agua
/
Monitoreo del Ambiente
/
Inhibidores de la Colinesterasa
/
Tilapia
Límite:
Animals
País/Región como asunto:
Mexico
Idioma:
En
Revista:
Mar Environ Res
Asunto de la revista:
BIOLOGIA
/
SAUDE AMBIENTAL
/
TOXICOLOGIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
México
Pais de publicación:
Reino Unido