Clinical, histopathologic, and therapeutic aspects of subepidermal autoimmune bullous diseases with IgG on the floor of salt-split skin.
Int J Dermatol
; 40(4): 268-72, 2001 Apr.
Article
en En
| MEDLINE
| ID: mdl-11454083
BACKGROUND: About 12% of patients with subepidermal autoimmune bullous disease and immunoglobulin G (IgG) at the dermal-epidermal junction present diseases other than bullous pemphigoid. MATERIALS AND METHODS: We report the clinical, histopathologic, and therapeutic aspects of eight cases of subepidermal bullous disorder with IgG on the floor of salt-split skin. RESULTS: A predominant neutrophilic infiltrate was detected in six of the eight patients. In one patient, the inflammatory infiltrate was neutrophilic and eosinophilic in the same proportion. A good response to dapsone alone or combined with prednisone was observed in six patients. CONCLUSIONS: The salt-split skin direct immunofluorescence test is useful for its diagnostic and therapeutic implications.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piel
/
Enfermedades Autoinmunes
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Inmunoglobulina G
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Enfermedades Cutáneas Vesiculoampollosas
Límite:
Adult
/
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Dermatol
Año:
2001
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Reino Unido