Isolation of the fibrocrystalline body, a structure present in haloarchaeal species, from Halobacterium salinarum.
Extremophiles
; 5(3): 169-75, 2001 Jun.
Article
en En
| MEDLINE
| ID: mdl-11453460
An organized structure, the fibrocrystalline body (FB), has been isolated from the archaeon Halobacterium salinarum. The structure is also present in, and can be isolated from, other extreme halophilic archaea. FB is present in the cytoplasm during the exponential growth and early stationary phases. This structure is affected by vincristine, an antitumoral drug, which targets tubulin. The drug causes fragmentation of the FB, changes in the cell shape, and growth inhibition. Taken together, these results point toward an important role in the life of the cell for this highly organized structure.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cuerpos de Inclusión
/
Halobacterium salinarum
Idioma:
En
Revista:
Extremophiles
Asunto de la revista:
BIOLOGIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Alemania