An outbreak of fulminant hepatitis delta in the Waorani, an indigenous people of the Amazon basin of Ecuador.
Am J Trop Med Hyg
; 63(3-4): 209-13, 2000.
Article
en En
| MEDLINE
| ID: mdl-11388517
An outbreak of delta hepatitis occurred during 1998 among the Waorani of the Amazon basin of Ecuador. Among 58 people identified with jaundice, 79% lived in four of 22 Waorani communities. Serum hepatitis B surface antigen (HBsAg) was found in the sera of 54% of the jaundiced persons, and 14% of asymptomatic persons. Ninety-five percent of 105 asymptomatic Waorani had hepatitis B core (HBc) IgG antibody, versus 98% of 51 with jaundice. These data confirm that hepatitis B virus (HBV) infection is highly endemic among the Waorani. Sixteen of 23 (70%) HBsAg carriers identified at the onset of the epidemic had serologic markers for hepatitis D virus (HDV) infection. All 16 were jaundiced, where as only two of seven (29%) with negative HDV serology were jaundiced (P = .0006). The delta cases clustered in families, 69% were children and most involved superinfection of people chronically infected with HBV. The data suggest that HDV spread rapidly by a horizontal mode of transmission other than by the sexual route.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hepatitis D
/
Virus de la Hepatitis Delta
/
Brotes de Enfermedades
/
Fallo Hepático
Tipo de estudio:
Etiology_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
País/Región como asunto:
America do sul
/
Ecuador
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
2000
Tipo del documento:
Article
País de afiliación:
Ecuador
Pais de publicación:
Estados Unidos