Evaluation of the role of routine serial cranial computed tomography in the management of children with human immunodeficiency virus infection.
Pediatr AIDS HIV Infect
; 8(1): 15-22, 1997 Feb.
Article
en En
| MEDLINE
| ID: mdl-11361507
OBJECTIVE: To review the impact of routine follow-up cranial computed tomography (CT) scans on the management of children with human immunodeficiency virus (HIV) infection. DESIGN: Longitudinal data collected from 58 HIV-infected children followed in one center for mean of 3.8 +/- 1.8 years. SETTING: HIV/AIDS pediatric program following over 90% of the identified HIV-infected children in one region in Canada. RESULTS: The baseline CT scans showed intracranial abnormalities in 35 of 58 children (60%). In five children with basal ganglia calcifications (BGC) without cerebral atrophy, there has not been progressive encephalopathy. For the 43 children who had serial CT scans for routine follow-up, 34 (79%) had changes in the scans that were concordant with the clinical assessment. In all but five children with progressive ventricular and sulcal dilatation on CT scan, there was simultaneous clinical evidence of encephalopathy. Those five children were already on antiretroviral therapy, and therapy was not changed in response to the CT scan findings. CONCLUSION: Baseline CT scans provide useful diagnostic and prognostic information. Further research is needed to evaluate the role of cranial CT imaging in the management of pediatric HIV encephalopathy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tomografía Computarizada por Rayos X
/
Complejo SIDA Demencia
/
Cuidados Posteriores
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
Idioma:
En
Revista:
Pediatr AIDS HIV Infect
Asunto de la revista:
PEDIATRIA
/
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Año:
1997
Tipo del documento:
Article
Pais de publicación:
Estados Unidos