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Placental and fetal pulsatility indices in gestational diabetes mellitus.
Fadda, G M; D'Antona, D; Ambrosini, G; Cherchi, P L; Nardelli, G B; Capobianco, G; Dessole, S.
Afiliación
  • Fadda GM; Department of Pharmacology, Gynecology and Obstetrics, University of Sassari, Sassari, Italy.
J Reprod Med ; 46(4): 365-70, 2001 Apr.
Article en En | MEDLINE | ID: mdl-11354838
OBJECTIVE: To assess the usefulness of placental and fetal Doppler velocimetry in the surveillance of gestational diabetes mellitus (GDM). STUDY DESIGN: We studied 89 patients with GDM. All fetuses underwent umbilical, fetal descending thoracic aorta and fetal middle cerebral artery pulsatility index (PI) assessment. Doppler results were not used for management. We correlated PI with route of delivery and with the following perinatal complications: small size for gestational age, cesarean section (CS) for acute fetal distress (AFD), respiratory distress syndrome, hyperbilirubinemia, hypocalcemia, hypoglycemia, macrosomia and stay in a neonatal intensive care unit. RESULTS: Seventy-seven patients (87%) had normal Doppler measurements, while 12 (13%) showed one or more abnormal measurements. The greatest incidence of CS for AFD (42% vs. 16%, P < .001), as well as neonatal hyperbilirubinemia (25% vs. 10%, P < .001) and hypoglycemia (25% vs. 5%, P < .001) was reported among the women with abnormal Doppler measurements. CONCLUSION: Fetal placental hemodynamics are normal in most cases of GDM. In a small percentage of cases we observed abnormal fetal placental PI associated with a higher incidence of perinatal complications. Hence, the finding of abnormal PI must induce the physician to carry out more intensive obstetric care of women with GDM.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Placenta / Diabetes Gestacional / Enfermedades Fetales / Feto Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Newborn / Pregnancy Idioma: En Revista: J Reprod Med Año: 2001 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Placenta / Diabetes Gestacional / Enfermedades Fetales / Feto Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Newborn / Pregnancy Idioma: En Revista: J Reprod Med Año: 2001 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos