Multiple mobile promoter regions for the rare carbapenem resistance gene of Bacteroides fragilis.
J Bacteriol
; 183(11): 3531-5, 2001 Jun.
Article
en En
| MEDLINE
| ID: mdl-11344163
Two novel insertion sequences (IS), IS1187 and IS1188, are described upstream from the carbapenem resistance gene cfiA in strains of Bacteroides fragilis. Mapping, with the RACE procedure, of transcription start sites of cfiA in these and two other previously reported IS showed that transcription of this rarely encountered gene is initiated close to a variety of B. fragilis consensus promoter sequences, as recently defined (D. P. Bayley, E. R. Rocha, and C. J. Smith, FEMS Microbiol. Lett. 193:149-154, 2000). In the cases of IS1186 and IS1188, these sequences overlap with putative Esigma(70) promoter sequences, while in IS942 and IS1187 such sequences can be observed either upstream or downstream of the B. fragilis promoters.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Bacterianas
/
Bacteroides fragilis
/
Beta-Lactamasas
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Elementos Transponibles de ADN
/
Carbapenémicos
/
Regiones Promotoras Genéticas
Idioma:
En
Revista:
J Bacteriol
Año:
2001
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Estados Unidos