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Insulin and somatostatin releasing islet cell tumor caused hypoglycemia.
Karasawa, Y; Mochizuki, T; Kawa, S; Aoki, Y; Ueno, T; Watanabe, T; Kawasaki, S; Miyagawa, S; Itoh, N; Tamai, C; Sakurai, A; Kiyosawa, K.
Afiliación
  • Karasawa Y; Department of Internal Medicine 2, Shinshu University Medical School, Matsumoto.
Intern Med ; 40(4): 324-30, 2001 Apr.
Article en En | MEDLINE | ID: mdl-11334393
We report a hypoglycemic case with normal insulin levels, which was caused by an islet cell tumor that was releasing insulin and somatostatin. A fasting test suggested the over secretion of insulin. Moreover, this hypoglycemia was enhanced by the inhibitory effect of somatostatin on the secretion of insulin counter-regulatory hormones, such as glucagon, in addition to the autonomous secretion of insulin from the tumor. In cases of hypoglycemia with apparently normal insulin levels, the measurement of somatostatin and various provocative tests are recommended. Arterial stimulation venous sampling (ASVS) was useful to detect the location of this functioning islet cell tumor.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Somatostatina / Adenoma de Células de los Islotes Pancreáticos / Hipoglucemia / Insulina Límite: Adult / Humans Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2001 Tipo del documento: Article Pais de publicación: Japón
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Somatostatina / Adenoma de Células de los Islotes Pancreáticos / Hipoglucemia / Insulina Límite: Adult / Humans Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2001 Tipo del documento: Article Pais de publicación: Japón