[Addition of clonidine to 0.5% lidocaine for intravenous locoregional anesthesia]. / Adjonction de clonidine à la lidocaïne à 0,5% pour anesthésie locorégionale intraveineuse.
Ann Fr Anesth Reanim
; 20(3): 255-9, 2001 Mar.
Article
en Fr
| MEDLINE
| ID: mdl-11332061
OBJECTIVE: Evaluate the effect of the addition of clonidine to lidocaine on postoperative pain after intravenous regional anaesthesia. STUDY DESIGN: Double blind prospective study. PATIENTS AND METHODS: Forty-five patients were randomly allocated to two groups: group 1 (n = 25) receiving 3 mg.kg-1 of lidocaine 0.5% added to saline and group 2 (n = 20) receiving 3 mg.kg-1 of lidocaine 0.5% added to clonidine (150 micrograms). Postoperative analgesia was assessed using a visual analogue pain score (VAPS) and the time to first analgesic request. The incidence of side effects after tourniquet release was noted. Analysis of variance, Kruskall Wallis and chi 2 tests were used for statistical analysis. A p-value of < 0.05 was considered significant. RESULTS: Age, ASA class, duration and type of surgery, tourniquet time and sensory block duration were comparable for the two groups. The time to first antalgic request after deflation of tourniquet was similar in the two groups (38 +/- 15 min versus 44 +/- 19 min), while VAPS score was lower (p < 0.05) in the clonidine group (5.2 versus 6.8). The incidence of side effects was comparable in the two groups. CONCLUSION: The addition of clonidine (150 micrograms) to lidocaine for intravenous regional anaesthesia improved postoperative analgesia but in a limited and short-lasting manner.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dolor Postoperatorio
/
Clonidina
/
Anestesia Intravenosa
/
Anestesia Local
/
Anestésicos Locales
/
Lidocaína
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Fr
Revista:
Ann Fr Anesth Reanim
Año:
2001
Tipo del documento:
Article
País de afiliación:
Marruecos
Pais de publicación:
Francia