Opioid poorly-responsive cancer pain. Part 3. Clinical strategies to improve opioid responsiveness.

Mercadante, S; Portenoy, R K

Mercadante, S; Portenoy, R K.

Afiliación

Mercadante S; Anesthesia and Intensive Care Unit & Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, Palermo, Italy.

J Pain Symptom Manage ; 21(4): 338-54, 2001 Apr.

Article en En | MEDLINE | ID: mdl-11312049

RESUMEN

Some pain syndromes may be difficult to treat due to a poor response to opioids. This situation demands a range of alternative measures, including the use of adjuvant drugs with independent effects, such as antidepressants, sodium channel-blocking agents, steroids and anti-inflammatory drugs (NSAIDs); drugs that reduce opioid side effects; and drugs that enhance analgesia produced by opioids, such as N-methyl-D-aspartate (NMDA) antagonists, calcium channel antagonists, and clonidine. Other approaches, including opioid trials, neural blockade when necessary, and psychological interventions, also may be useful.

Asunto(s)

Analgésicos Opioides/uso terapéutico; Neoplasias/terapia; Cuidados Paliativos; Analgésicos Opioides/administración & dosificación; Analgésicos Opioides/efectos adversos; Resistencia a Medicamentos; Sinergismo Farmacológico; Humanos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cuidados Paliativos / Analgésicos Opioides / Neoplasias Límite: Humans Idioma: En Revista: J Pain Symptom Manage Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA / TERAPEUTICA Año: 2001 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

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