Evaluation of the chronic inhalation toxocity of a manganese oxide aerosol. II. Clinical observations, hematology, clinical chemistry and histopathology.
Am Ind Hyg Assoc J
; 40(4): 322-9, 1979 Apr.
Article
en En
| MEDLINE
| ID: mdl-112847
Monkeys and rats were exposed to 11.6, 112.5, or 1152 microgram Mn/m3 as an Mn3O4 aerosol twenty-four hours per day for nine months. Various serum biochemical, and hematologic evaluations were conducted on both specie. Body weight gain was accelerated in rats exposed to 1152 microgram Mn/m3. Hemoglobin concentrations were slightly elevated for both sexes and both specie exposed to 1152 microgram Mn/m3; however, the effect may not be directly related to Mn. Some evidence of hypophosphatemia was observed. No exposure related effects were demonstrated by organ weight or histopathologic observations.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Respiración
/
Encéfalo
/
Hemoglobinas
/
Intoxicación por Manganeso
Límite:
Animals
Idioma:
En
Revista:
Am Ind Hyg Assoc J
Año:
1979
Tipo del documento:
Article
Pais de publicación:
Estados Unidos