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Two cases of 8p trisomy in one sibship.
Clin Genet ; 7(4): 328-33, 1975 Apr.
Article en En | MEDLINE | ID: mdl-1126055
Two cases of 8p trisomy in one sibship are presented. The father was a balanced carrier of a translocation rcp (8;13) (p11; q34). Case 1 was a 2-year -old boy with multiple minor anomalies and severe mental retardation. Giemsa banding studies revealed that he was trisomic for the greater part of 8p (8p11 yields pter). When his mother became pregnant again, amniocentesis was carried out in the 17th week of gestation. The fetus (Case 2) was shown to have the same 8p trisomy as Case 1. The pregnancy was terminated in the 22nd week. An autopsy revealed no major anomalies. Clinical features of cases with 8 and 8p trisomy are reviewed briefly.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trisomía / Cromosomas Humanos 6-12 y X Límite: Child, preschool / Female / Humans / Male / Pregnancy Idioma: En Revista: Clin Genet Año: 1975 Tipo del documento: Article Pais de publicación: Dinamarca
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trisomía / Cromosomas Humanos 6-12 y X Límite: Child, preschool / Female / Humans / Male / Pregnancy Idioma: En Revista: Clin Genet Año: 1975 Tipo del documento: Article Pais de publicación: Dinamarca