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Usefulness of handgrip to improve ibutilide efficacy in organizing atrial electrical activity during atrial fibrillation.
Pitzalis, M V; Grimaldi, M; Anaclerio, M; Iacoviello, M; Luzzi, G; Forleo, C; Rizzon, P.
Afiliación
  • Pitzalis MV; Institute of Cardiology, University of Bari, Italy. mariavittoria.pitzalis@cardio.uniba.it
Am J Cardiol ; 87(6): 798-801, A8-9, 2001 Mar 15.
Article en En | MEDLINE | ID: mdl-11249910
We analyzed the effect of handgrip on atrial electrical activity during atrial fibrillation (AF) by recording right and left atrial activity in 15 patients with persistent AF under baseline conditions and after saline and ibutilide infusions. The handgrip test for 15 seconds, which was always associated with a significant increase in mean atrial cycle length, was recorded in both atria (right atrium: saline vs saline + handgrip 141 +/- 29 vs 171 +/- 24 ms, p <0.001; ibutilide vs ibutilide + handgrip: 197 +/- 43 vs 221 +/- 39 ms, p <0.005). Handgrip favorably modifies atrial electrophysiologic properties during AF.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Sulfonamidas / Función Atrial / Fuerza de la Mano / Contracción Isométrica / Antiarrítmicos Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Am J Cardiol Año: 2001 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Sulfonamidas / Función Atrial / Fuerza de la Mano / Contracción Isométrica / Antiarrítmicos Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Am J Cardiol Año: 2001 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos