In vitro development of resistance to six quinolones in Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus.

Boos, M; Mayer, S; Fischer, A; Köhrer, K; Scheuring, S; Heisig, P; Verhoef, J; Fluit, A C; Schmitz, F J

Boos, M; Mayer, S; Fischer, A; Köhrer, K; Scheuring, S; Heisig, P; Verhoef, J; Fluit, A C; Schmitz, F J.

Afiliación

Boos M; Institute for Medical Microbiology and Virology, Heinrich-Heine Universität Düsseldorf, Düsseldorf, Germany.

Antimicrob Agents Chemother ; 45(3): 938-42, 2001 Mar.

Article en En | MEDLINE | ID: mdl-11181385

RESUMEN

Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus isolates were exposed to subinhibitory MICs of ciprofloxacin, sparfloxacin, gatifloxacin, moxifloxacin, clinafloxacin, and gemifloxacin during a 10-day period. Subculturing led to resistance development, regardless of the initial potencies of the quinolones. None of the quinolones was associated with a significantly slower rate of resistance development.

Asunto(s)

Antiinfecciosos/farmacología; Staphylococcus aureus/efectos de los fármacos; Streptococcus pneumoniae/efectos de los fármacos; Streptococcus pyogenes/efectos de los fármacos; Farmacorresistencia Microbiana/fisiología; Fluoroquinolonas; Humanos; Pruebas de Sensibilidad Microbiana

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus aureus / Streptococcus pneumoniae / Streptococcus pyogenes / Antiinfecciosos Límite: Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2001 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos

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