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Modern methods for diagnosis and monitoring of nephrotoxicity during antitumor therapy with platinum derivatives.
Lyubimova, N V; Topchieva, S V; Averinova, S G; Kashkadaeva, A V; Gorbunova, V A; Shiryaev, S V; Kushlinskii, N E.
Afiliación
  • Lyubimova NV; N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow.
Bull Exp Biol Med ; 130(9): 886-91, 2000 Sep.
Article en En | MEDLINE | ID: mdl-11177273
Chemotherapy is an important method of antitumor therapy. Nephrotoxicity characteristic of many cytostatics, including platinum compounds, is a serious complication limiting the drug dose [4,5,7-9]. Platinum derivatives, in particular, cisplatin, are drugs of choice in the treatment of the majority of solid tumors. However, cisplatin induces a dose-dependent toxic damage to the kidneys [5,7,8,10].
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Cisplatino / Riñón / Enfermedades Renales / Antineoplásicos Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Bull Exp Biol Med Año: 2000 Tipo del documento: Article Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Cisplatino / Riñón / Enfermedades Renales / Antineoplásicos Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Bull Exp Biol Med Año: 2000 Tipo del documento: Article Pais de publicación: Estados Unidos