Chromosomal changes in a dedifferentiated chondrosarcoma: a case report and review of the literature.
Cancer Genet Cytogenet
; 124(2): 105-11, 2001 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-11172900
The chromosome abnormalities observed in a dedifferentiated chondrosarcoma are reported. A new molecular cytogenetic technique, spectral karyotyping, was used to identify and confirm structural rearrangements in this case. A review of the literature revealed that nine cases have been reported, in eight of which a complete description of the cytogenetic abnormalities was described. Structural aberrations were most frequently reported in chromosomes 1 and 9, and chromosomes 7 and 19 were most frequently observed to be involved in numerical aberrations (trisomy and tetrasomy). In chondrosarcomas, structural aberrations in chromosomes 1 and 9 and trisomy or tetrasomy of chromosome 7 are among the more frequently observed aberrations.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Condrosarcoma
/
Aberraciones Cromosómicas
/
Neoplasias Femorales
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Cancer Genet Cytogenet
Año:
2001
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos