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Chromosomal changes in a dedifferentiated chondrosarcoma: a case report and review of the literature.
O'Malley, D P; Opheim, K E; Barry, T S; Chapman, D B; Emond, M J; Conrad, E U; Norwood, T H.
Afiliación
  • O'Malley DP; Department of Pathology, Loma Linda University Medical Center, Loma Linda, CA, USA.
Cancer Genet Cytogenet ; 124(2): 105-11, 2001 Jan 15.
Article en En | MEDLINE | ID: mdl-11172900
The chromosome abnormalities observed in a dedifferentiated chondrosarcoma are reported. A new molecular cytogenetic technique, spectral karyotyping, was used to identify and confirm structural rearrangements in this case. A review of the literature revealed that nine cases have been reported, in eight of which a complete description of the cytogenetic abnormalities was described. Structural aberrations were most frequently reported in chromosomes 1 and 9, and chromosomes 7 and 19 were most frequently observed to be involved in numerical aberrations (trisomy and tetrasomy). In chondrosarcomas, structural aberrations in chromosomes 1 and 9 and trisomy or tetrasomy of chromosome 7 are among the more frequently observed aberrations.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Condrosarcoma / Aberraciones Cromosómicas / Neoplasias Femorales Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Cancer Genet Cytogenet Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Condrosarcoma / Aberraciones Cromosómicas / Neoplasias Femorales Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Cancer Genet Cytogenet Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos