Molecular markers of tumor initiation and progression.

Porter, P L

Porter, P L.

Afiliación

Porter PL; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, and Department of Pathology, University of Washington Medical Center, 1100 Fairview N, Seattle, Washington 98109, USA. pporter@fhcrc.org

Curr Opin Genet Dev ; 11(1): 60-3, 2001 Feb.

Article en En | MEDLINE | ID: mdl-11163152

RESUMEN

Of the hundreds of genes and proteins reported to be altered in human cancers, only a few are sufficiently central to warrant translation into diagnostic or therapeutic tools. Three recent developments have the potential to alter radically the discovery of molecular markers: the compendium of human genes; the advent of technologies that provide the means to identify simultaneously several known and unknown genes and proteins; and an appreciation of the critical processes involved in tumor initiation and progression.

Asunto(s)

Transformación Celular Neoplásica/genética; ADN de Neoplasias/genética; Análisis de Secuencia por Matrices de Oligonucleótidos; Transformación Celular Neoplásica/metabolismo; ADN de Neoplasias/metabolismo; Genes Supresores de Tumor; Genes cdc; Marcadores Genéticos; Humanos; Pérdida de Heterocigocidad; Oncogenes

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN de Neoplasias / Transformación Celular Neoplásica / Análisis de Secuencia por Matrices de Oligonucleótidos Límite: Humans Idioma: En Revista: Curr Opin Genet Dev Asunto de la revista: GENETICA Año: 2001 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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