The use of lepirudin for anticoagulation in patients with heparin-induced thrombocytopenia during major vascular surgery.

Sun, Y; Greilich, P E; Wilson, S I; Jackson, M R; Whitten, C W

Sun, Y; Greilich, P E; Wilson, S I; Jackson, M R; Whitten, C W.

Afiliación

Sun Y; Department of Anesthesiology & Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas.

Anesth Analg ; 92(2): 344-6, 2001 Feb.

Article en En | MEDLINE | ID: mdl-11159229

RESUMEN

The method of anticoagulation in patients undergoing major vascular surgery with a history of heparin-induced thrombocytopenia (HIT) is controversial. We present two cases in which a bolus only technique using recombinant hirudin (Lepirudin or Refludan) was used successfully in patients with HIT scheduled for vascular surgery.

Asunto(s)

Anticoagulantes/farmacología; Heparina/efectos adversos; Hirudinas/análogos & derivados; Hirudinas/farmacología; Proteínas Recombinantes/farmacología; Trombocitopenia/inducido químicamente; Anciano; Humanos; Masculino; Persona de Mediana Edad; Tiempo de Tromboplastina Parcial; Procedimientos Quirúrgicos Vasculares

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombocitopenia / Proteínas Recombinantes / Heparina / Hirudinas / Anticoagulantes Límite: Aged / Humans / Male / Middle aged Idioma: En Revista: Anesth Analg Año: 2001 Tipo del documento: Article Pais de publicación: Estados Unidos

Buscar en Google

Añadir a Mi BVS

Imprimir

XML

PubMed Links