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RNA polymerase--promoter recognition. Specific features of electrostatic potential of "early" T4 phage DNA promoters.
Kamzolova, S G; Sivozhelezov, V S; Sorokin, A A; Dzhelyadin, T R; Ivanova, N N; Polozov, R V.
Afiliación
  • Kamzolova SG; Institute of Cell Biophysics of RAS, Pushchino Moscow Region, Russia. kamzolova@mail.ru
J Biomol Struct Dyn ; 18(3): 325-34, 2000 Dec.
Article en En | MEDLINE | ID: mdl-11149509
Comparative analysis of electrostatic potential distribution for "early" T4 phage promoters was undertaken, along with calculation of topography of electrostatic potential around the native and ADP-ribosylated C-terminal domain of RNA polymerase alpha-subunit. The data obtained indicate that there is specific difference in the patterns of electrostatic potential distribution in far upstream regions of T4 promoters differing by their response to ADP-ribosylation of RNA polymerase. A specific change in profiles of electrostatic potential distribution for the native and ADP-ribosylated forms of RNA polymerase alpha-subunit was observed suggesting that this factor may be responsible for modulating T4 promoter activities in response to the enzyme modification.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Polimerasas Dirigidas por ADN / ADN Viral / Regiones Promotoras Genéticas / Bacteriófago T4 Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biomol Struct Dyn Año: 2000 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Reino Unido
Buscar en Google
Añadir a Mi BVS
Imprimir
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PubMed Links

Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Polimerasas Dirigidas por ADN / ADN Viral / Regiones Promotoras Genéticas / Bacteriófago T4 Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biomol Struct Dyn Año: 2000 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Reino Unido