Complex rearrangement of chromosomes 6 and 11 as the sole anomaly in atypical teratoid/rhabdoid tumors of the central nervous system.
Cancer Genet Cytogenet
; 122(2): 149-52, 2000 Oct 15.
Article
en En
| MEDLINE
| ID: mdl-11106829
Atypical teratoid/rhabdoid tumor of the central nervous system is a rare childhood tumor with a distinct histologic appearance and an aggressive clinical course. Few tumors have been analyzed cytogenetically. The only consistent chromosomal abnormality identified in some of these tumors has been monosomy or deletions of chromosome 22; in others, a normal chromosome 22 was present. The authors report an atypical teratoid/rhabdoid neoplasm of the central nervous system with a novel complex rearrangement affecting chromosomes 6 and 11 as the sole anomaly. The involvement of region 11p15 could be important in the pathogenesis of this entity.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Teratoma
/
Cromosomas Humanos Par 6
/
Cromosomas Humanos Par 11
/
Aberraciones Cromosómicas
/
Neoplasias del Sistema Nervioso Central
/
Tumor Rabdoide
Tipo de estudio:
Prognostic_studies
Límite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
Cancer Genet Cytogenet
Año:
2000
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Estados Unidos