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Urinary excretion of glycosaminoglycans in patients with isolated nocturnal enuresis or combined with diurnal incontinence.
Ferrara, P; Rigante, D; Lambert-Gardini, S; Salvaggio, E; Ricci, R; Chiozza, M L; Antuzzi, D.
Afiliación
  • Ferrara P; Department of Paediatrics, Università Cattolica Sacro Cuore, Rome, Italy. pietro.ferrara@mailcity.com
BJU Int ; 86(7): 824-5, 2000 Nov.
Article en En | MEDLINE | ID: mdl-11069407
OBJECTIVE: To determine variations in the amount of glycosaminoglycans (GAGs) excreted by patients with nocturnal enuresis and/or diurnal incontinence. PATIENTS, SUBJECTS AND METHODS: The study included 27 patients (aged 5-15 years) with nocturnal enuresis and/or diurnal incontinence, and 27 healthy age-matched children. Their urinary GAG excretion was assessed over 24 h using the sodium tetraborate-carbazole method. RESULTS: Patients with nocturnal enuresis and/or diurnal incontinence had higher mean values of urinary GAG excretion than age-matched controls. There were significant differences in GAG excretion between those with nocturnal enuresis and diurnal incontinence and those with nocturnal enuresis alone. CONCLUSIONS: GAG excretion in patients with nocturnal enuresis and/or diurnal incontinence was significantly higher than in normal children, suggesting that measuring urinary GAGs may be useful in evaluating physiopathological conditions of the bladder wall, and hence in monitoring potential damage in the bladder mucosa.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Incontinencia Urinaria / Enuresis / Glicosaminoglicanos Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: BJU Int Asunto de la revista: UROLOGIA Año: 2000 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Incontinencia Urinaria / Enuresis / Glicosaminoglicanos Límite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: BJU Int Asunto de la revista: UROLOGIA Año: 2000 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido