The construction of the first balancer chromosome for the Mediterranean fruit fly, Ceratitis capitata.

Gourzi, P; Gubb, D; Livadaras, Y; Caceres, C; Franz, G; Savakis, C; Zacharopoulou, A

Gourzi, P; Gubb, D; Livadaras, Y; Caceres, C; Franz, G; Savakis, C; Zacharopoulou, A.

Afiliación

Gourzi P; Department of Biology, University of Patras, Greece.

Mol Gen Genet ; 264(1-2): 127-36, 2000 Sep.

Article en En | MEDLINE | ID: mdl-11016842

RESUMEN

The construction of the first balancer chromosome, FiM1, for the medfly Ceratitis capitata is described. This chromosome has three overlapping pericentric inversions and is marked with dominant and recessive mutations. The inversion breakpoints of FiM1 suppress recombination throughout the length of the fifth chromosome, allowing lethal mutations to be recovered and maintained. This chromosome will provide a powerful tool for the manipulation of laboratory stocks, in particular, the recovery of new mutant and transgenic strains. We demonstrate the use of FiM1 for the recovery and maintenance of chromosomes carrying lethal mutations.

Asunto(s)

Cromosomas; Dípteros/genética; Animales; Aberraciones Cromosómicas; Inversión Cromosómica; Femenino; Fertilidad/genética; Genes Letales; Genes Recesivos; Marcadores Genéticos; Técnicas Genéticas; Masculino; Mutación; Recombinación Genética

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromosomas / Dípteros Límite: Animals Idioma: En Revista: Mol Gen Genet Año: 2000 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Alemania

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