Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.

Holla, B S; Rao, B S; Shridhara, K; Akberali, P M

Holla, B S; Rao, B S; Shridhara, K; Akberali, P M.

Afiliación

Holla BS; Department of P.G. Studies and Research in Chemistry, Mangalore University, Mangalagangothri, India. hollabs@yahoo.com

Farmaco ; 55(5): 338-44, 2000 May.

Article en En | MEDLINE | ID: mdl-10983278

RESUMEN

A series of 3-substituted-4-[5-(2,4-dichlorophenyl)-2-furfurylidine]amino-5-me rcapto-1, 2,4-triazoles (3) are synthesised. Aminomethylation of 3 with formaldehyde and a primary/secondary amine furnished Mannich bases 4 and 5. Both Schiff bases 3 and Mannich bases 4 and 5 are characterised on the basis of IR, 1H NMR, mass spectral data and elemental analysis. All the newly synthesised compounds are tested for their antibacterial activities. Some of the selected compounds are also tested for their fungicidal and herbicidal properties.

Asunto(s)

Antiinfecciosos/síntesis química; Antiinfecciosos/farmacología; Furaldehído/análogos & derivados; Furaldehído/química; Furanos/síntesis química; Furanos/farmacología; Bases de Mannich/química; Antiinfecciosos/química; Furanos/química; Herbicidas/síntesis química; Herbicidas/química; Herbicidas/farmacología; Estructura Molecular; Análisis Espectral

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Furaldehído / Furanos / Bases de Mannich / Antiinfecciosos Idioma: En Revista: Farmaco Asunto de la revista: FARMACOLOGIA / QUIMICA Año: 2000 Tipo del documento: Article País de afiliación: India Pais de publicación: Francia

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