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The validity of the ECLAM index for the retrospective evaluation of disease activity in systemic lupus erythematosus.
Mosca, M; Bencivelli, W; Vitali, C; Carrai, P; Neri, R; Bombardieri, S.
Afiliación
  • Mosca M; Department of Internal Medicine, University of Pisa, Italy. marta@sssup.it
Lupus ; 9(6): 445-50, 2000.
Article en En | MEDLINE | ID: mdl-10981649
AIM: To determine whether the European Consensus Lupus Activity Measurement Index (ECLAM) can be used to evaluate disease activity in patients retrospectively from the data provided in their clinical charts. METHODS: The ECLAM score was calculated twice in a series of 64 consecutive SLE patients: first for each patient during the course of a standard clinical evaluation (direct-ECLAM), and then one to two weeks later solely on the basis of the data provided in the patient's clinical chart (chartECLAM). The scorings for each patient were performed by two different assessors. RESULTS: The direct-ECLAM and chart-ECLAM scores were highly correlated (Spearman's rank correlation coefficient = 0.86). The regression line was not significantly different from the identity line (t-test). The Pearson's coefficient was 0.88. The interobserver variability of the chart-ECLAM showed a low inter-rater variability. CONCLUSION: ECLAM could represent a valid and reliable instrument for the retrospective analysis of disease activity in SLE patients.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Lupus Eritematoso Sistémico Tipo de estudio: Observational_studies Límite: Female / Humans / Male Idioma: En Revista: Lupus Asunto de la revista: REUMATOLOGIA Año: 2000 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Lupus Eritematoso Sistémico Tipo de estudio: Observational_studies Límite: Female / Humans / Male Idioma: En Revista: Lupus Asunto de la revista: REUMATOLOGIA Año: 2000 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido