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Comparative immunohistochemical distribution of connexin 37 and connexin 43 throughout folliculogenesis in the bovine ovary.
Nuttinck, F; Peynot, N; Humblot, P; Massip, A; Dessy, F; Fléchon, J E.
Afiliación
  • Nuttinck F; Unité de Biologie du Développement, Institut National de Recherche Agronomique, Jouy-en-Josas, France.
Mol Reprod Dev ; 57(1): 60-6, 2000 Sep.
Article en En | MEDLINE | ID: mdl-10954857
Among gap junctional proteins previously identified in the mouse ovary, connexins (Cx) Cx37 and Cx43 appeared to be essential for normal follicular growth. The aim of this work was to detect Cx37 expression in the bovine ovary, then to quantify and compare its follicular distribution pattern with that of Cx43 using quantitative analysis of immunofluorescently labeled ovary sections viewed with a confocal laser scanning microscope. Cx37 immunoreactivity was detected in bovine ovarian follicles and was predominantly localized at preantral stages. Unlike follicular Cx43 expression which was restricted to granulosa cells, Cx37 staining was observed in both oocyte and granulosa cell compartments. While no changes were seen during early follicular growth, the level of Cx37 expression decreased significantly at the onset of antral cavity formation (P
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conexinas / Conexina 43 / Folículo Ovárico Límite: Animals Idioma: En Revista: Mol Reprod Dev Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Año: 2000 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conexinas / Conexina 43 / Folículo Ovárico Límite: Animals Idioma: En Revista: Mol Reprod Dev Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Año: 2000 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos