Detection of antifungal activity in Portulaca oleracea by a single-cell bioassay system.

Oh, K B; Chang, I M; Hwang, K J; Mar, W

Oh, K B; Chang, I M; Hwang, K J; Mar, W.

Afiliación

Oh KB; Natural Products Research Institute, Seoul National University, Korea.

Phytother Res ; 14(5): 329-32, 2000 Aug.

Article en En | MEDLINE | ID: mdl-10925396

RESUMEN

The antifungal activity of Portulaca oleracea extracts against hyphal growth of various fungi was evaluated in real time using an automatic single-cell bioassay system. Target organisms were the filamentous fungi Aspergillus and Trichophyton and the yeast Candida. A colony of test fungi was in contact with the assay medium, or assay medium containing plant extract, in sequence. The antifungal activity of each fraction of P. oleracea was evaluated based on the dynamic hyphal growth response curves of test fungi. A crude sample obtained by EtOAc extract showed a specific and marked activity against dermatophytes of the genera Trichophyton.

Asunto(s)

Antifúngicos/farmacología; Hongos Mitospóricos/efectos de los fármacos; Extractos Vegetales/farmacología; Plantas Medicinales/química; Antifúngicos/química; Aspergillus/efectos de los fármacos; Candida/efectos de los fármacos; Humanos; Pruebas de Sensibilidad Microbiana; Extractos Vegetales/química; Trichophyton/efectos de los fármacos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plantas Medicinales / Extractos Vegetales / Hongos Mitospóricos / Antifúngicos Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Phytother Res Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2000 Tipo del documento: Article Pais de publicación: Reino Unido

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