Do automated red cell exchanges relieve priapism in patients with sickle cell anemia?
Ther Apher
; 4(3): 256-8, 2000 Jun.
Article
en En
| MEDLINE
| ID: mdl-10910030
Priapism is a dramatic, painful complication for some men afflicted by sickle cell anemia. Although the natural history remains unclear, many believe replacing the patient's abnormal red blood cells (RBCs) with normal RBCs by apheresis is effective. However, no controlled trials have demonstrated its effectiveness. We exchanged 7 men after medical management failed. All procedures reduced sickle hemoglobin levels to < 30%. Two patients underwent emergency automated red cell exchanges without any detumescence or reduction of pain. The remaining 5 patients were exchanged non-emergently; 4 experienced no detumescence or relief of pain. One adult experienced resolution 8 h postexchange. However, he had a history of "stuttering" priapism. All required decompression procedures. Automated RBC exchanges were not effective in achieving detumescence or reducing pain.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Priapismo
/
Citaféresis
/
Eritrocitos
/
Anemia de Células Falciformes
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Child
/
Humans
/
Male
Idioma:
En
Revista:
Ther Apher
Asunto de la revista:
HEMATOLOGIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos