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Branch retinal vein occlusion associated with the 20210 G-to-A prothrombin variant.
Peris Martínez, C; Aviñó Martínez, J; Díaz-Llopis, M; España Gregori, E; Menezo, J L; Vayá, A.
Afiliación
  • Peris Martínez C; Department of Ophthalmology, University Hospital "La Fe", Valencia, Spain.
Eur J Ophthalmol ; 10(2): 177-9, 2000.
Article en En | MEDLINE | ID: mdl-10887932
PURPOSE: To describe a case of branch retinal vein occlusion (BRVO) in a patient who tested positive for the 20210 A allele of the prothrombin (PT) gene. METHODS: A 48-year-old man had visual loss in the right eye secondary to BRVO confirmed by ophthalmoscopy and fluorescein angiography. His medical history was not remarkable for common risk factors for retinal occlusive diseases. RESULTS: Laboratory tests for hypercoagulability were positive for PT 20210 A variant. The patient's family tested negative for the PT variant. CONCLUSIONS: Laboratory tests for coagulopathy, including the PT 20210 A variant, should be added to the examination of patients with central or BRVO, especially if most common risk factors for thrombosis have been excluded.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Variación Genética / Oclusión de la Vena Retiniana / Protrombina / Mutación Puntual Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans / Male / Middle aged Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2000 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Variación Genética / Oclusión de la Vena Retiniana / Protrombina / Mutación Puntual Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans / Male / Middle aged Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2000 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos