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HIV-1 transmission in injection paraphernalia: heating drug solutions may inactivate HIV-1.
Clatts, M C; Heimer, R; Abdala, N; Goldsamt, L A; Sotheran, J L; Anderson, K T; Gallo, T M; Hoffer, L D; Luciano, P A; Kyriakides, T.
Afiliación
  • Clatts MC; National Development and Research Institutes, Inc., New York, New York 10048, USA. michael.clatts@ndri.org
J Acquir Immune Defic Syndr ; 22(2): 194-9, 1999 Oct 01.
Article en En | MEDLINE | ID: mdl-10843535
In response to recent concerns about risk of HIV-1 transmission from drug injection paraphernalia such as cookers, ethnographic methods were used to develop a descriptive typology of the paraphernalia and practices used to prepare and inject illegal drugs. Observational data were then applied in laboratory studies in which a quantitative HIV-1 microculture assay was used to measure the recovery of infectious HIV-1 in cookers. HIV-1 survival inside cookers was a function of the temperature achieved during preparation of drug solutions; HIV-1 was inactivated once temperature exceeded, on average, 65 degrees C. Although different types of cookers, volumes, and heat sources affected survival times, heating cookers 15 seconds or longer reduced viable HIV-1 below detectable levels.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Abuso de Sustancias por Vía Intravenosa / Contaminación de Equipos / VIH-1 Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: J Acquir Immune Defic Syndr Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 1999 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Abuso de Sustancias por Vía Intravenosa / Contaminación de Equipos / VIH-1 Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: J Acquir Immune Defic Syndr Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 1999 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos