Lactate-induced rage and panic in a select group of subjects who perpetrate acts of domestic violence.
Biol Psychiatry
; 47(9): 804-12, 2000 May 01.
Article
en En
| MEDLINE
| ID: mdl-10812039
BACKGROUND: Perpetrators of domestic violence frequently report symptoms of autonomic arousal and a sense of fear and/or loss of control at the time of the violence. Since many of these symptoms are also associated with panic attacks, we hypothesized that perpetrators of domestic violence and patients with panic attacks may share similar exaggerated fear-related behaviors. To test this hypothesis, we employed the panicogenic agent sodium lactate to examine the response of perpetrators to anxiety fear induced by a chemical agent. METHODS: Using a double-blind, placebo-controlled design, we infused 0.5 mol/L sodium lactate or placebo over 20 min on separate days to a select group of subjects who perpetrate acts of domestic violence and two nonviolent comparison groups. We compared their behavioral, neuroendocrine, and physiologic responses. RESULTS: Lactate administration elicited intense emotional responses in the perpetrators of domestic violence. Perpetrators evidenced more lactate-induced rage and panic and showed greater changes in speech, breathing, and motor activity than did nonviolent control subjects. There were no significant differences between the groups for any neuroendocrine or physiologic measure. CONCLUSIONS: These results are consistent with our hypothesis that some perpetrators of domestic violence have exaggerated fear-related behavioral responses.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pánico
/
Furor
/
Violencia Doméstica
/
Ácido Láctico
Tipo de estudio:
Clinical_trials
Aspecto:
Determinantes_sociais_saude
/
Equity_inequality
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Biol Psychiatry
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos