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Lipoprotein(a) status in coronary heart disease.
Khan, M A; Baseer, A.
Afiliación
  • Khan MA; Department of Biochemistry, Jinnah Postgraduate Medical Centre, Karachi.
J Pak Med Assoc ; 50(2): 47-50, 2000 Feb.
Article en En | MEDLINE | ID: mdl-10769521
OBJECTIVE: To compare the magnitude of lipid, and lipoproteins, especially the lipoprotein(a) [Lp(a)], in controls and patients with coronary heart disease (CHD). METHODS: Serum total cholesterol, triglyceride, HDL-C, LDL-C, VLDL-C, apo A1, apo B, and Lp(a) levels were determined in 37 patients with CHD and 25 age matched control subjects. RESULTS: A significant difference (P < 0.001) in lipid and apolipoprotein ratios were found. Lp(a) and other lipid parameters were found significantly high (P < 0.001) with the exception of HDL-C and apo B which were significantly low (P < 0.001) in CHD patients. CONCLUSIONS: Elevated levels of Lp(a) suggest not only its role in atherogenesis, leading to CHD, but also that Lp(a) should be given due consideration while assessing CHD risk.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lipoproteína(a) / Enfermedad Coronaria Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Pak Med Assoc Año: 2000 Tipo del documento: Article Pais de publicación: Pakistán
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lipoproteína(a) / Enfermedad Coronaria Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Pak Med Assoc Año: 2000 Tipo del documento: Article Pais de publicación: Pakistán