[Chemoresistance in ovarian cancer. State of the art and future prospects]. / La chemioresistenza nel carcinoma dell'ovaio. Stato dell'arte e prospettive future.
Minerva Ginecol
; 51(12): 483-99, 1999 Dec.
Article
en It
| MEDLINE
| ID: mdl-10767997
Aim of this study was to provide a review of the basic mechanisms of drug resistance in ovarian cancer and novel strategies to modulate drug resistance. Relevant articles published through August 1999 were identified using the Medline data base. Publications identified by the search were reviewed and evaluated critically for their relevance to drug resistance in ovarian cancer. Ovarian cancer patients have high response rates to initial chemotherapy after cytoreductive surgery. However, most will develop resistance to chemotherapy during the course of their treatment. There are multiple mechanisms resulting in drug resistance. Strategies to modulate drug resistance include dose intensity, various pharmacologic agents, and gene therapy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Antineoplásicos
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
It
Revista:
Minerva Ginecol
Año:
1999
Tipo del documento:
Article
Pais de publicación:
Italia